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ITF2357 transactivates Id3 and regulate TGFβ/BMP7 signaling pathways to attenuate corneal fibrosis
Corneal fibrosis is often seen in patients with ocular trauma and infection that compromises corneal transparency resulting in vision loss. Treatment strategies including NSAIDs, steroids, MMC and corneal transplants have shown tremendous success but with several side effects and cellular toxicity....
Autores principales: | Lim, Rayne R., Tan, Alison, Liu, Yu-Chi, Barathi, Veluchamy A., Mohan, Rajiv R., Mehta, Jodhbir S., Chaurasia, Shyam S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750002/ https://www.ncbi.nlm.nih.gov/pubmed/26865052 http://dx.doi.org/10.1038/srep20841 |
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