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Myosin di-phosphorylation and peripheral actin bundle formation as initial events during endothelial barrier disruption

The phosphorylation of the 20-kD myosin light chain (MLC) and actin filament formation play a key role in endothelial barrier disruption. MLC is either mono- or di-phosphorylated (pMLC and ppMLC) at T18 or S19. The present study investigated whether there are any distinct roles of pMLC and ppMLC in...

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Detalles Bibliográficos
Autores principales: Hirano, Mayumi, Hirano, Katsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750094/
https://www.ncbi.nlm.nih.gov/pubmed/26863988
http://dx.doi.org/10.1038/srep20989