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Myosin di-phosphorylation and peripheral actin bundle formation as initial events during endothelial barrier disruption
The phosphorylation of the 20-kD myosin light chain (MLC) and actin filament formation play a key role in endothelial barrier disruption. MLC is either mono- or di-phosphorylated (pMLC and ppMLC) at T18 or S19. The present study investigated whether there are any distinct roles of pMLC and ppMLC in...
Autores principales: | Hirano, Mayumi, Hirano, Katsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750094/ https://www.ncbi.nlm.nih.gov/pubmed/26863988 http://dx.doi.org/10.1038/srep20989 |
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