Distinct genomic and epigenomic features demarcate hypomethylated blocks in colon cancer

BACKGROUND: Large mega base-pair genomic regions show robust alterations in DNA methylation levels in multiple cancers. A vast majority of these regions are hypomethylated in cancers. These regions are generally enriched for CpG islands, Lamin Associated Domains and Large organized chromatin lysine...

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Detalles Bibliográficos
Autores principales: Sharmin, Mahfuza, Bravo, Héctor Corrada, Hannenhalli, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750190/
https://www.ncbi.nlm.nih.gov/pubmed/26868017
http://dx.doi.org/10.1186/s12885-016-2128-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750190/
https://www.ncbi.nlm.nih.gov/pubmed/26868017
http://dx.doi.org/10.1186/s12885-016-2128-1

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