Distinct genomic and epigenomic features demarcate hypomethylated blocks in colon cancer

BACKGROUND: Large mega base-pair genomic regions show robust alterations in DNA methylation levels in multiple cancers. A vast majority of these regions are hypomethylated in cancers. These regions are generally enriched for CpG islands, Lamin Associated Domains and Large organized chromatin lysine...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharmin, Mahfuza, Bravo, Héctor Corrada, Hannenhalli, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750190/
https://www.ncbi.nlm.nih.gov/pubmed/26868017
http://dx.doi.org/10.1186/s12885-016-2128-1

Ejemplares similares

Ejemplares similares