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Spectroscopic and Crystallographic Evidence for the Role of a Water-Containing H-Bond Network in Oxidase Activity of an Engineered Myoglobin

[Image: see text] Heme-copper oxidases (HCOs) catalyze efficient reduction of oxygen to water in biological respiration. Despite progress in studying native enzymes and their models, the roles of non-covalent interactions in promoting this activity are still not well understood. Here we report EPR s...

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Detalles Bibliográficos
Autores principales: Petrik, Igor D., Davydov, Roman, Ross, Matthew, Zhao, Xuan, Hoffman, Brian, Lu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750474/
https://www.ncbi.nlm.nih.gov/pubmed/26716352
http://dx.doi.org/10.1021/jacs.5b12004