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Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)

Targeted cancer therapies are used to inhibit the growth, progression, and metastasis of the tumor by interfering with specific molecular targets and are currently the focus of anticancer drug development. Protein kinase B, also known as Akt, plays a central role in many types of cancer and has been...

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Detalles Bibliográficos
Autores principales: NITULESCU, GEORGE MIHAI, MARGINA, DENISA, JUZENAS, PETRAS, PENG, QIAN, OLARU, OCTAVIAN TUDOREL, SALOUSTROS, EMMANOUIL, FENGA, CONCETTINA, SPANDIDOS, DEMETRIOS A., LIBRA, MASSIMO, TSATSAKIS, ARISTIDIS M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750533/
https://www.ncbi.nlm.nih.gov/pubmed/26698230
http://dx.doi.org/10.3892/ijo.2015.3306