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Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)
Targeted cancer therapies are used to inhibit the growth, progression, and metastasis of the tumor by interfering with specific molecular targets and are currently the focus of anticancer drug development. Protein kinase B, also known as Akt, plays a central role in many types of cancer and has been...
Autores principales: | NITULESCU, GEORGE MIHAI, MARGINA, DENISA, JUZENAS, PETRAS, PENG, QIAN, OLARU, OCTAVIAN TUDOREL, SALOUSTROS, EMMANOUIL, FENGA, CONCETTINA, SPANDIDOS, DEMETRIOS A., LIBRA, MASSIMO, TSATSAKIS, ARISTIDIS M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750533/ https://www.ncbi.nlm.nih.gov/pubmed/26698230 http://dx.doi.org/10.3892/ijo.2015.3306 |
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