Minimal hepatic glucose-6-phosphatase-α activity required to sustain survival and prevent hepatocellular adenoma formation in murine glycogen storage disease type Ia

Glycogen storage disease type Ia (GSD-Ia), characterized by impaired glucose homeostasis and chronic risk of hepatocellular adenoma (HCA), is caused by a deficiency in glucose-6-phosphatase-α (G6Pase-α or G6PC) activity. In a previous 70–90 week-study, we showed that a recombinant adeno-associated v...

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Detalles Bibliográficos
Autores principales: Lee, Young Mok, Kim, Goo-Young, Pan, Chi-Jiunn, Mansfield, Brian C., Chou, Janice Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
SI:Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750588/
https://www.ncbi.nlm.nih.gov/pubmed/26937391
http://dx.doi.org/10.1016/j.ymgmr.2015.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750588/
https://www.ncbi.nlm.nih.gov/pubmed/26937391
http://dx.doi.org/10.1016/j.ymgmr.2015.03.001

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