3-Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial-mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Glycolysis is the primary method utilized by cancer cells to produce the energy (adenosine triphosphate, ATP) required for cell proliferation. Therefore, inhibition of glycolysis may inhibit tumor growth. We previously found that both 3-bromopyruvate (3-BrPA) and sodium citrate (SCT) can inhibit gly...

Descripción completa

Detalles Bibliográficos
Autores principales: WANG, TING-AN, ZHANG, XIAO-DONG, GUO, XING-YU, XIAN, SHU-LIN, LU, YUN-FEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750747/
https://www.ncbi.nlm.nih.gov/pubmed/26708213
http://dx.doi.org/10.3892/or.2015.4511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750747/
https://www.ncbi.nlm.nih.gov/pubmed/26708213
http://dx.doi.org/10.3892/or.2015.4511

Ejemplares similares