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Diethylstilbestrol Regulates the Expression of LGR8 in Mouse Gubernaculum Testis Cells

BACKGROUND: Hormonal effects on the gubernaculum can affect testicular descent. Diethylstilbestrol (DES) is a nonsteroidal synthetic estrogen that disrupts the outgrowth of gubernaculums, leading to testis maldescent. However, the underlying mechanisms remain elusive. MATERIAL/METHODS: The gubernacu...

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Detalles Bibliográficos
Autores principales: Duan, Shouxing, Jiang, Xuewu, Zhang, Xuan, Xie, Lei, Sun, Zongbo, Ma, Shuhua, Li, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750751/
https://www.ncbi.nlm.nih.gov/pubmed/26855023
http://dx.doi.org/10.12659/MSM.895089