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A matrix metalloproteinase inhibitor enhances anti-cytotoxic T lymphocyte antigen-4 antibody immunotherapy in breast cancer by reprogramming the tumor microenvironment

Anti-cytotoxic T lymphocyte antigen-4 (CTLA-4) treatment is effective for the treatment of primary tumors, but not sufficient for the treatment of metastatic tumors, likely owing to the effects of the tumor microenvironment. In this study, we aimed to determine the therapeutic effects of combined tr...

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Detalles Bibliográficos
Autores principales: LI, MINGYUE, XING, SHUGANG, ZHANG, HAIYING, SHANG, SIQI, LI, XIANGXIANG, REN, BO, LI, GAIYUN, CHANG, XIAONA, LI, YILEI, LI, WEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750755/
https://www.ncbi.nlm.nih.gov/pubmed/26752000
http://dx.doi.org/10.3892/or.2016.4547