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Mesoglycan attenuates VSMC proliferation through activation of AMP-activated protein kinase and mTOR
BACKGROUND: Vascular smooth muscle cells (VSMC) proliferation contributes significantly to intimal thickening in atherosclerosis and restenosis diseases. Platelet derived growth factor (PDGF) has been implicated in VSMC proliferation though the activation of multiple growth-promoting signals. Mesogl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750809/ https://www.ncbi.nlm.nih.gov/pubmed/26893937 http://dx.doi.org/10.1186/s40885-016-0037-x |