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Synergistic Malaria Parasite Killing by Two Types of Plasmodial Surface Anion Channel Inhibitors

Malaria parasites increase their host erythrocyte’s permeability to a broad range of ions and organic solutes. The plasmodial surface anion channel (PSAC) mediates this uptake and is an established drug target. Development of therapies targeting this channel is limited by several problems including...

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Detalles Bibliográficos
Autores principales: Pain, Margaret, Fuller, Alexandra W., Basore, Katherine, Pillai, Ajay D., Solomon, Tsione, Bokhari, Abdullah A. B., Desai, Sanjay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750852/
https://www.ncbi.nlm.nih.gov/pubmed/26866812
http://dx.doi.org/10.1371/journal.pone.0149214