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Resident CAPS on dense-core vesicles docks and primes vesicles for fusion

The Ca(2+)-dependent exocytosis of dense-core vesicles in neuroendocrine cells requires a priming step during which SNARE protein complexes assemble. CAPS (aka CADPS) is one of several factors required for vesicle priming; however, the localization and dynamics of CAPS at sites of exocytosis in live...

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Detalles Bibliográficos
Autores principales: Kabachinski, Greg, Kielar-Grevstad, D. Michelle, Zhang, Xingmin, James, Declan J., Martin, Thomas F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750925/
https://www.ncbi.nlm.nih.gov/pubmed/26700319
http://dx.doi.org/10.1091/mbc.E15-07-0509