Inferring Growth Control Mechanisms in Growing Multi-cellular Spheroids of NSCLC Cells from Spatial-Temporal Image Data

We develop a quantitative single cell-based mathematical model for multi-cellular tumor spheroids (MCTS) of SK-MES-1 cells, a non-small cell lung cancer (NSCLC) cell line, growing under various nutrient conditions: we confront the simulations performed with this model with data on the growth kinetic...

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Detalles Bibliográficos
Autores principales: Jagiella, Nick, Müller, Benedikt, Müller, Margareta, Vignon-Clementel, Irene E., Drasdo, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750943/
https://www.ncbi.nlm.nih.gov/pubmed/26866479
http://dx.doi.org/10.1371/journal.pcbi.1004412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750943/
https://www.ncbi.nlm.nih.gov/pubmed/26866479
http://dx.doi.org/10.1371/journal.pcbi.1004412

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