Mesenchymal Stromal Cells Prevent Renal Fibrosis in a Rat Model of Unilateral Ureteral Obstruction by Suppressing the Renin-Angiotensin System via HuR

We studied Mesenchymal Stromal Cells (MSC) effects in experimental Unilateral Ureteral Obstruction (UUO), a fibrogenic renal disease. Rats were divided in 5 groups: sham, UUO, MSC treated-UUO, ACEi treated-UUO, MSC+ACEi treated- UUO. Data were collected at 1, 7, 21 days. UUO induced monocyte renal i...

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Detalles Bibliográficos
Autores principales: Gregorini, Marilena, Corradetti, Valeria, Rocca, Chiara, Pattonieri, Eleonora Francesca, Valsania, Teresa, Milanesi, Samantha, Serpieri, Nicoletta, Bedino, Giulia, Esposito, Pasquale, Libetta, Carmelo, Avanzini, Maria Antonietta, Mantelli, Melissa, Ingo, Daniela, Peressini, Sabrina, Albertini, Riccardo, Dal Canton, Antonio, Rampino, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750962/
https://www.ncbi.nlm.nih.gov/pubmed/26866372
http://dx.doi.org/10.1371/journal.pone.0148542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750962/
https://www.ncbi.nlm.nih.gov/pubmed/26866372
http://dx.doi.org/10.1371/journal.pone.0148542

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