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The Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage Response
The DNA damage response (DDR) is a conglomerate of pathways designed to detect DNA damage and signal its presence to cell cycle checkpoints and to the repair machinery, allowing the cell to pause and mend the damage, or if the damage is too severe, to trigger apoptosis or senescence. Various DDR bra...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750969/ https://www.ncbi.nlm.nih.gov/pubmed/26867009 http://dx.doi.org/10.1371/journal.ppat.1005420 |