Cargando…
The Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage Response
The DNA damage response (DDR) is a conglomerate of pathways designed to detect DNA damage and signal its presence to cell cycle checkpoints and to the repair machinery, allowing the cell to pause and mend the damage, or if the damage is too severe, to trigger apoptosis or senescence. Various DDR bra...
Autores principales: | Brestovitsky, Anna, Nebenzahl-Sharon, Keren, Kechker, Peter, Sharf, Rakefet, Kleinberger, Tamar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750969/ https://www.ncbi.nlm.nih.gov/pubmed/26867009 http://dx.doi.org/10.1371/journal.ppat.1005420 |
Ejemplares similares
-
The adenovirus E4orf4 protein targets PP2A to the ACF chromatin-remodeling factor and induces cell death through regulation of SNF2h-containing complexes
por: Brestovitsky, Anna, et al.
Publicado: (2011) -
Adenovirus E4orf4 protein induces PP2A-dependent growth arrest in Saccharomyces cerevisiae and interacts with the anaphase-promoting complex/cyclosome
por: Kornitzer, Daniel, et al.
Publicado: (2001) -
Selective elimination of cancer cells by the adenovirus E4orf4 protein in a Drosophila cancer model: a new paradigm for cancer therapy
por: Rosen, Helit, et al.
Publicado: (2019) -
Mechanisms of Cancer Cell Killing by the Adenovirus E4orf4 Protein
por: Kleinberger, Tamar
Publicado: (2015) -
The adenovirus E4orf4 protein induces a unique mode of cell death while inhibiting classical apoptosis
por: Pechkovsky, Antonina, et al.
Publicado: (2013)