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Angiotensin II Type 2 Receptor Decreases Transforming Growth Factor-β Type II Receptor Expression and Function in Human Renal Proximal Tubule Cells

Transforming growth factor-β (TGF-β), via its receptors, induces epithelial-mesenchymal transition (EMT) and plays an important role in the development of renal tubulointersitial fibrosis. Angiotensin II type 2 receptor (AT(2)R), which mediates beneficial renal physiological functions, has received...

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Detalles Bibliográficos
Autores principales: Guo, Hui-Lin, Liao, Xiao-Hui, Liu, Qi, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750982/
https://www.ncbi.nlm.nih.gov/pubmed/26867007
http://dx.doi.org/10.1371/journal.pone.0148696