Structural Study of the HD-PTP Bro1 Domain in a Complex with the Core Region of STAM2, a Subunit of ESCRT-0

EGFR is a key player in cell proliferation and survival signaling, and its sorting into MVBs for eventual lysosomal degradation is controlled by the coordination of multiple ESCRT complexes on the endosomal membrane. HD-PTP is a cytosolic protein tyrosine phosphatase, and is associated with EGFR tra...

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Detalles Bibliográficos
Autores principales: Lee, Juhyeon, Oh, Kyoung-Jin, Lee, Dasom, Kim, Bo Yeon, Choi, Joon Sig, Ku, Bonsu, Kim, Seung Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751086/
https://www.ncbi.nlm.nih.gov/pubmed/26866605
http://dx.doi.org/10.1371/journal.pone.0149113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751086/
https://www.ncbi.nlm.nih.gov/pubmed/26866605
http://dx.doi.org/10.1371/journal.pone.0149113

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