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Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis
Hypoxia in tumors is primarily a pathophysiologic consequence of structurally and functionally disturbed microcirculation with inadequate supply of oxygen. Tumor hypoxia is strongly associated with tumor propagation, malignant progression, and resistance to therapy. Aberrant epigenetic regulation pl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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China Medical University
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751095/ https://www.ncbi.nlm.nih.gov/pubmed/26869355 http://dx.doi.org/10.7603/s40681-016-0001-9 |