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Caveolae as a target to quench autoinduction of the metastatic phenotype in lung cancer

PURPOSE: Mevalonate pathway inhibitors are potentially useful chemotherapeutic agents showing growth inhibition and pro-apoptotic effects in cancer cells. The effects of statins and bisphosphonates on cancer growth are attributed to a reduction in protein isoprenylation. Post-translational modificat...

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Detalles Bibliográficos
Autor principal: Garnett, David John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751176/
https://www.ncbi.nlm.nih.gov/pubmed/26573510
http://dx.doi.org/10.1007/s00432-015-2074-3