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Caveolae as a target to quench autoinduction of the metastatic phenotype in lung cancer
PURPOSE: Mevalonate pathway inhibitors are potentially useful chemotherapeutic agents showing growth inhibition and pro-apoptotic effects in cancer cells. The effects of statins and bisphosphonates on cancer growth are attributed to a reduction in protein isoprenylation. Post-translational modificat...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751176/ https://www.ncbi.nlm.nih.gov/pubmed/26573510 http://dx.doi.org/10.1007/s00432-015-2074-3 |