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Efficient Rejoining of DNA Double-Strand Breaks despite Increased Cell-Killing Effectiveness following Spread-Out Bragg Peak Carbon-Ion Irradiation

Radiotherapy of solid tumors with charged particles holds several advantages in comparison to photon therapy; among them conformal dose distribution in the tumor, improved sparing of tumor-surrounding healthy tissue, and an increased relative biological effectiveness (RBE) in the tumor target volume...

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Detalles Bibliográficos
Autores principales: Averbeck, Nicole B., Topsch, Jana, Scholz, Michael, Kraft-Weyrather, Wilma, Durante, Marco, Taucher-Scholz, Gisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751252/
https://www.ncbi.nlm.nih.gov/pubmed/26904506
http://dx.doi.org/10.3389/fonc.2016.00028