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A Simulation Model of Periarterial Clearance of Amyloid-β from the Brain

The accumulation of soluble and insoluble amyloid-β (Aβ) in the brain indicates failure of elimination of Aβ from the brain with age and Alzheimer's disease (AD). There is a variety of mechanisms for elimination of Aβ from the brain. They include the action of microglia and enzymes together wit...

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Detalles Bibliográficos
Autores principales: Diem, Alexandra K., Tan, Mingyi, Bressloff, Neil W., Hawkes, Cheryl, Morris, Alan W. J., Weller, Roy O., Carare, Roxana O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751273/
https://www.ncbi.nlm.nih.gov/pubmed/26903861
http://dx.doi.org/10.3389/fnagi.2016.00018