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Divergent evolution of vitamin B9 binding underlies Juno-mediated adhesion of mammalian gametes

The interaction between egg and sperm is the first necessary step of fertilization in all sexually reproducing organisms. A decade-long search for a protein pair mediating this event in mammals culminated in the identification of the glycosylphosphatidylinositol (GPI)-anchored glycoprotein Juno as t...

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Detalles Bibliográficos
Autores principales: Han, Ling, Nishimura, Kaoru, Sadat Al Hosseini, Hamed, Bianchi, Enrica, Wright, Gavin J., Jovine, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751342/
https://www.ncbi.nlm.nih.gov/pubmed/26859261
http://dx.doi.org/10.1016/j.cub.2015.12.034