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Divergent evolution of vitamin B9 binding underlies Juno-mediated adhesion of mammalian gametes
The interaction between egg and sperm is the first necessary step of fertilization in all sexually reproducing organisms. A decade-long search for a protein pair mediating this event in mammals culminated in the identification of the glycosylphosphatidylinositol (GPI)-anchored glycoprotein Juno as t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751342/ https://www.ncbi.nlm.nih.gov/pubmed/26859261 http://dx.doi.org/10.1016/j.cub.2015.12.034 |