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Starvation Induces Proteasome Autophagy with Different Pathways for Core and Regulatory Particles
The proteasome is responsible for the degradation of many cellular proteins. If and how this abundant and normally stable complex is degraded by cells is largely unknown. Here we show that in yeast, upon nitrogen starvation, proteasomes are targeted for vacuolar degradation through autophagy. Using...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751371/ https://www.ncbi.nlm.nih.gov/pubmed/26670610 http://dx.doi.org/10.1074/jbc.M115.699124 |