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Starvation Induces Proteasome Autophagy with Different Pathways for Core and Regulatory Particles

The proteasome is responsible for the degradation of many cellular proteins. If and how this abundant and normally stable complex is degraded by cells is largely unknown. Here we show that in yeast, upon nitrogen starvation, proteasomes are targeted for vacuolar degradation through autophagy. Using...

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Detalles Bibliográficos
Autores principales: Waite, Kenrick A., Mota-Peynado, Alina De-La, Vontz, Gabrielle, Roelofs, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751371/
https://www.ncbi.nlm.nih.gov/pubmed/26670610
http://dx.doi.org/10.1074/jbc.M115.699124