Plasma EGFR T790M ctDNA status is associated with clinical outcome in advanced NSCLC patients with acquired EGFR-TKI resistance

EGFR T790M mutation occurs in half of non-small cell lung cancer (NSCLC) patients with acquired EGFR-TKI (TKI) resistance, based on tumor re-biopsies using an invasive clinical procedure. Here, we dynamically monitored T790M mutation in circulating tumor DNA (ctDNA) using serial plasma samples from...

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Detalles Bibliográficos
Autores principales: Zheng, D., Ye, X., Zhang, M. Z., Sun, Y., Wang, J. Y., Ni, J., Zhang, H. P., Zhang, L., Luo, J., Zhang, J., Tang, L., Su, B., Chen, G., Zhu, G., Gu, Y., Xu, J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751431/
https://www.ncbi.nlm.nih.gov/pubmed/26867973
http://dx.doi.org/10.1038/srep20913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751431/
https://www.ncbi.nlm.nih.gov/pubmed/26867973
http://dx.doi.org/10.1038/srep20913

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