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Four-Week Repeated Intravenous Dose Toxicity and Toxicokinetic Study of TS-DP2, a Novel Human Granulocyte Colony Stimulating Factor in Rats

TS-DP2 is a recombinant human granulocyte colony stimulating factor (rhG-CSF) manufactured by TS Corporation. We conducted a four-week study of TS-DP2 (test article) in repeated intravenous doses in male and female Sprague-Dawley (SD) rats. Lenograstim was used as a reference article and was adminis...

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Detalles Bibliográficos
Autores principales: Lee, JooBuom, Lee, Kyungsun, Choe, Keunbum, Jung, Hyunseob, Cho, Hyunseok, Choi, Kiseok, Kim, Taegon, Kim, Seojin, Lee, Hyeong-Seok, Cha, Mi-Jin, Song, Si-Whan, Lee, Chul Kyu, Chun, Gie-Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society Of Toxicology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751447/
https://www.ncbi.nlm.nih.gov/pubmed/26877840
http://dx.doi.org/10.5487/TR.2015.31.4.371