Prostaglandin I(2) Attenuates Prostaglandin E(2)-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent Mechanism

Cyclooxygenase-2 (COX-2) has been recently identified as being involved in the pathogenesis of Alzheimer’s disease (AD). However, the role of an important COX-2 metabolic product, prostaglandin (PG) I(2), in AD development remains unknown. Using mouse-derived astrocytes as well as APP/PS1 transgenic...

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Detalles Bibliográficos
Autores principales: Wang, Pu, Guan, Pei-Pei, Yu, Xin, Zhang, Li-Chao, Su, Ya-Nan, Wang, Zhan-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751455/
https://www.ncbi.nlm.nih.gov/pubmed/26869183
http://dx.doi.org/10.1038/srep20879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751455/
https://www.ncbi.nlm.nih.gov/pubmed/26869183
http://dx.doi.org/10.1038/srep20879

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