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Prostaglandin I(2) Attenuates Prostaglandin E(2)-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent Mechanism
Cyclooxygenase-2 (COX-2) has been recently identified as being involved in the pathogenesis of Alzheimer’s disease (AD). However, the role of an important COX-2 metabolic product, prostaglandin (PG) I(2), in AD development remains unknown. Using mouse-derived astrocytes as well as APP/PS1 transgenic...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751455/ https://www.ncbi.nlm.nih.gov/pubmed/26869183 http://dx.doi.org/10.1038/srep20879 |