CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response

Radiation has a limited but relevant role in the adjuvant therapy of gastric cancer (GC) patients. Since Chk1 plays a critical function in cellular response to genotoxic agents, we aimed to analyze the role of Chk1 in GC as a biomarker for radiotherapy resistance. We analyzed Chk1 expression in AGS...

Descripción completa

Detalles Bibliográficos
Autores principales: Bargiela-Iparraguirre, J., Prado-Marchal, L., Fernandez-Fuente, M., Gutierrez-González, A., Moreno-Rubio, J., Muñoz-Fernandez, M., Sereno, M., Sanchez-Prieto, R., Perona, R., Sanchez-Perez, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751465/
https://www.ncbi.nlm.nih.gov/pubmed/26867682
http://dx.doi.org/10.1038/srep21519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751465/
https://www.ncbi.nlm.nih.gov/pubmed/26867682
http://dx.doi.org/10.1038/srep21519

Ejemplares similares