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CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response

Radiation has a limited but relevant role in the adjuvant therapy of gastric cancer (GC) patients. Since Chk1 plays a critical function in cellular response to genotoxic agents, we aimed to analyze the role of Chk1 in GC as a biomarker for radiotherapy resistance. We analyzed Chk1 expression in AGS...

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Detalles Bibliográficos
Autores principales:	Bargiela-Iparraguirre, J., Prado-Marchal, L., Fernandez-Fuente, M., Gutierrez-González, A., Moreno-Rubio, J., Muñoz-Fernandez, M., Sereno, M., Sanchez-Prieto, R., Perona, R., Sanchez-Perez, I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751465/ https://www.ncbi.nlm.nih.gov/pubmed/26867682 http://dx.doi.org/10.1038/srep21519

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