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A synergistic blocking effect of Mg(2+) and spermine on the inward rectifier K(+) (Kir2.1) channel pore
Inward rectifier K(+) channels (Kir2.1) exhibit an extraordinary rectifying feature in the current–voltage relationship. We have previously showed that the bundle–crossing region of the transmembrane domain constitutes the crucial segment responsible for the polyamine block. In this study, we demons...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751470/ https://www.ncbi.nlm.nih.gov/pubmed/26869275 http://dx.doi.org/10.1038/srep21493 |