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Using contrast patterns between true complexes and random subgraphs in PPI networks to predict unknown protein complexes
Most protein complex detection methods utilize unsupervised techniques to cluster densely connected nodes in a protein-protein interaction (PPI) network, in spite of the fact that many true complexes are not dense subgraphs. Supervised methods have been proposed recently, but they do not answer why...
Autores principales: | Liu, Quanzhong, Song, Jiangning, Li, Jinyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751475/ https://www.ncbi.nlm.nih.gov/pubmed/26868667 http://dx.doi.org/10.1038/srep21223 |
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