Cargando…

Hypoxia-mediated autophagic flux inhibits silver nanoparticle-triggered apoptosis in human lung cancer cells

Solid tumors are frequently associated with resistance to chemotherapy because the fraction of hypoxic tumor cells is substantial. To understand the underlying mechanism of hypoxia on silver nanoparticle (AgNPs)-induced apoptosis, the expression of hypoxia-inducible factor (HIF)-1α, a hallmark of hy...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeong, Jae-Kyo, Gurunathan, Sangiliyandi, Kang, Min-Hee, Han, Jae Woong, Das, Joydeep, Choi, Yun-Jung, Kwon, Deug-Nam, Cho, Ssang-Goo, Park, Chankyu, Seo, Han Geuk, Song, Hyuk, Kim, Jin-Hoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751501/
https://www.ncbi.nlm.nih.gov/pubmed/26867977
http://dx.doi.org/10.1038/srep21688