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Radiosensitisation of human colorectal cancer cells by ruthenium(II) arene anticancer complexes

Some of the largest improvements in clinical outcomes for patients with solid cancers observed over the past 3 decades have been from concurrent treatment with chemotherapy and radiotherapy (RT). The lethal effects of RT on cancer cells arise primarily from damage to DNA. Ruthenium (Ru) is a transit...

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Detalles Bibliográficos
Autores principales: Carter, R, Westhorpe, A, Romero, MJ, Habtemariam, A, Gallevo, CR, Bark, Y, Menezes, N, Sadler, PJ, Sharma, RA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751532/
https://www.ncbi.nlm.nih.gov/pubmed/26867983
http://dx.doi.org/10.1038/srep20596