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Genome-Wide Analysis of the TORC1 and Osmotic Stress Signaling Network in Saccharomyces cerevisiae

The Target of Rapamycin kinase Complex I (TORC1) is a master regulator of cell growth and metabolism in eukaryotes. Studies in yeast and human cells have shown that nitrogen/amino acid starvation signals act through Npr2/Npr3 and the small GTPases Gtr1/Gtr2 (Rags in humans) to inhibit TORC1. However...

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Detalles Bibliográficos
Autores principales: Worley, Jeremy, Sullivan, Arron, Luo, Xiangxia, Kaplan, Matthew E., Capaldi, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751564/
https://www.ncbi.nlm.nih.gov/pubmed/26681516
http://dx.doi.org/10.1534/g3.115.025882