APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane

Mutations in adenomatous polyposis coli (APC) disrupt regulation of Wnt signaling, mitosis, and the cytoskeleton. We describe a new role for APC in the transport of mitochondria. Silencing of wild-type APC by small interfering RNA caused mitochondria to redistribute from the cell periphery to the pe...

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Detalles Bibliográficos
Autores principales: Mills, Kate M., Brocardo, Mariana G., Henderson, Beric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751598/
https://www.ncbi.nlm.nih.gov/pubmed/26658612
http://dx.doi.org/10.1091/mbc.E15-09-0632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751598/
https://www.ncbi.nlm.nih.gov/pubmed/26658612
http://dx.doi.org/10.1091/mbc.E15-09-0632

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