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Nerve growth factor stimulates axon outgrowth through negative regulation of growth cone actomyosin restraint of microtubule advance

Nerve growth factor (NGF) promotes growth, differentiation, and survival of sensory neurons in the mammalian nervous system. Little is known about how NGF elicits faster axon outgrowth or how growth cones integrate and transform signal input to motor output. Using cultured mouse dorsal root ganglion...

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Detalles Bibliográficos
Autores principales: Turney, Stephen G., Ahmed, Mostafa, Chandrasekar, Indra, Wysolmerski, Robert B., Goeckeler, Zoe M., Rioux, Robert M., Whitesides, George M., Bridgman, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751601/
https://www.ncbi.nlm.nih.gov/pubmed/26631553
http://dx.doi.org/10.1091/mbc.E15-09-0636