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By moonlighting in the nucleus, villin regulates epithelial plasticity

Villin is a tissue-specific, actin-binding protein involved in the assembly and maintenance of microvilli in polarized epithelial cells. Conversely, villin is also linked with the loss of epithelial polarity and gain of the mesenchymal phenotype in migrating, invasive cells. In this study, we descri...

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Detalles Bibliográficos
Autores principales: Patnaik, Srinivas, George, Sudeep P., Pham, Eric, Roy, Swati, Singh, Kanchan, Mariadason, John M., Khurana, Seema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751603/
https://www.ncbi.nlm.nih.gov/pubmed/26658611
http://dx.doi.org/10.1091/mbc.E15-06-0453