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By moonlighting in the nucleus, villin regulates epithelial plasticity
Villin is a tissue-specific, actin-binding protein involved in the assembly and maintenance of microvilli in polarized epithelial cells. Conversely, villin is also linked with the loss of epithelial polarity and gain of the mesenchymal phenotype in migrating, invasive cells. In this study, we descri...
Autores principales: | Patnaik, Srinivas, George, Sudeep P., Pham, Eric, Roy, Swati, Singh, Kanchan, Mariadason, John M., Khurana, Seema |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751603/ https://www.ncbi.nlm.nih.gov/pubmed/26658611 http://dx.doi.org/10.1091/mbc.E15-06-0453 |
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