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The alternate AP-1 adaptor subunit Apm2 interacts with the Mil1 regulatory protein and confers differential cargo sorting

Heterotetrameric adaptor protein complexes are important mediators of cargo protein sorting in clathrin-coated vesicles. The cell type–specific expression of alternate μ chains creates distinct forms of AP-1 with altered cargo sorting, but how these subunits confer differential function is unclear....

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Detalles Bibliográficos
Autores principales: Whitfield, Shawn T., Burston, Helen E., Bean, Björn D. M., Raghuram, Nandini, Maldonado-Báez, Lymarie, Davey, Michael, Wendland, Beverly, Conibear, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751606/
https://www.ncbi.nlm.nih.gov/pubmed/26658609
http://dx.doi.org/10.1091/mbc.E15-09-0621