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Heme Oxygenase-1 and 2 Common Genetic Variants and Risk for Multiple Sclerosis

Several neurochemical, neuropathological, and experimental data suggest a possible role of oxidative stress in the ethiopathogenesis of multiple sclerosis(MS). Heme-oxygenases(HMOX) are an important defensive mechanism against oxidative stress, and HMOX1 is overexpressed in the brain and spinal cord...

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Detalles Bibliográficos
Autores principales: Agúndez, José A. G., García-Martín, Elena, Martínez, Carmen, Benito-León, Julián, Millán-Pascual, Jorge, Díaz-Sánchez, María, Calleja, Patricia, Pisa, Diana, Turpín-Fenoll , Laura, Alonso-Navarro, Hortensia, Pastor, Pau, Ortega-Cubero, Sara, Ayuso-Peralta, Lucía, Torrecillas, Dolores, García-Albea, Esteban, Plaza-Nieto, José Francisco, Jiménez-Jiménez, Félix Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751624/
https://www.ncbi.nlm.nih.gov/pubmed/26868429
http://dx.doi.org/10.1038/srep20830