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Heme Oxygenase-1 and 2 Common Genetic Variants and Risk for Multiple Sclerosis
Several neurochemical, neuropathological, and experimental data suggest a possible role of oxidative stress in the ethiopathogenesis of multiple sclerosis(MS). Heme-oxygenases(HMOX) are an important defensive mechanism against oxidative stress, and HMOX1 is overexpressed in the brain and spinal cord...
Autores principales: | Agúndez, José A. G., García-Martín, Elena, Martínez, Carmen, Benito-León, Julián, Millán-Pascual, Jorge, Díaz-Sánchez, María, Calleja, Patricia, Pisa, Diana, Turpín-Fenoll , Laura, Alonso-Navarro, Hortensia, Pastor, Pau, Ortega-Cubero, Sara, Ayuso-Peralta, Lucía, Torrecillas, Dolores, García-Albea, Esteban, Plaza-Nieto, José Francisco, Jiménez-Jiménez, Félix Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751624/ https://www.ncbi.nlm.nih.gov/pubmed/26868429 http://dx.doi.org/10.1038/srep20830 |
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