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Organic Cation Transporter 1 (OCT1) mRNA expression in hepatocellular carcinoma as a biomarker for sorafenib treatment

BACKGROUND: The polyspecific organ cation transporter 1 (OCT1) is one of the most important active influx pumps for drugs like the kinase inhibitor sorafenib. The aim of this retrospective study was the definition of the role of intratumoral OCT1 mRNA expression in hepatocellular carcinoma (HCC) as...

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Detalles Bibliográficos
Autores principales: Grimm, Daniel, Lieb, Jonas, Weyer, Veronika, Vollmar, Johanna, Darstein, Felix, Lautem, Anja, Hoppe-Lotichius, Maria, Koch, Sandra, Schad, Arno, Schattenberg, Jörn M., Wörns, Marcus A., Weinmann, Arndt, Galle, Peter R., Zimmermann, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751638/
https://www.ncbi.nlm.nih.gov/pubmed/26872727
http://dx.doi.org/10.1186/s12885-016-2150-3