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Does primary neoadjuvant systemic therapy eradicate minimal residual disease? Analysis of disseminated and circulating tumor cells before and after therapy

BACKGROUND: Patients with breast cancer (BC) undergoing neoadjuvant chemotherapy (NACT) may experience metastatic relapse despite achieving a pathologic complete response. We analyzed patients with BC before and after NACT for disseminated tumor cells (DTCs) in the bone marrow(BM); comprehensively c...

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Detalles Bibliográficos
Autores principales: Kasimir-Bauer, Sabine, Bittner, Ann-Kathrin, König, Lisa, Reiter, Katharina, Keller, Thomas, Kimmig, Rainer, Hoffmann, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751719/
https://www.ncbi.nlm.nih.gov/pubmed/26868521
http://dx.doi.org/10.1186/s13058-016-0679-3