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A benchmark study on error-correction by read-pairing and tag-clustering in amplicon-based deep sequencing
BACKGROUND: The high error rate of next generation sequencing (NGS) restricts some of its applications, such as monitoring virus mutations and detecting rare mutations in tumors. There are two commonly employed sequencing library preparation strategies to improve sequencing accuracy by correcting se...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751728/ https://www.ncbi.nlm.nih.gov/pubmed/26868371 http://dx.doi.org/10.1186/s12864-016-2388-9 |