New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways

Signaling pathways regulated by the receptor CDCP1 play central roles in promoting cancer and in mediating resistance to chemo- and targeted-therapies. In this perspective we briefly summarize these findings as well as data demonstrating poorer outcomes for several malignancies that exhibit elevated...

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Detalles Bibliográficos
Autores principales: He, Yaowu, Harrington, Brittney S., Hooper, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751911/
https://www.ncbi.nlm.nih.gov/pubmed/26973855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751911/
https://www.ncbi.nlm.nih.gov/pubmed/26973855

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