Deriving Heterospecific Self-Assembling Protein–Protein Interactions Using a Computational Interactome Screen

Interactions between naturally occurring proteins are highly specific, with protein-network imbalances associated with numerous diseases. For designed protein–protein interactions (PPIs), required specificity can be notoriously difficult to engineer. To accelerate this process, we have derived pepti...

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Detalles Bibliográficos
Autores principales: Crooks, Richard O., Baxter, Daniel, Panek, Anna S., Lubben, Anneke T., Mason, Jody M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751974/
https://www.ncbi.nlm.nih.gov/pubmed/26655848
http://dx.doi.org/10.1016/j.jmb.2015.11.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751974/
https://www.ncbi.nlm.nih.gov/pubmed/26655848
http://dx.doi.org/10.1016/j.jmb.2015.11.022

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